Aberrant Neuregulin 1 Signaling in Amyotrophic Lateral Sclerosis
نویسندگان
چکیده
منابع مشابه
Aberrant neuregulin 1 signaling in amyotrophic lateral sclerosis.
Neuregulin 1 (NRG1) is a neuron-derived trophic molecule that supports axoglial and neuromuscular development through several alternatively spliced isoforms; its possible role in the pathogenesis and progression of amyotrophic lateral sclerosis (ALS) is not known. We analyzed the relationship of NRG1 isoform expression to glial cell activation and motor neuron loss in spinal cords of ALS patien...
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ژورنال
عنوان ژورنال: Journal of Neuropathology & Experimental Neurology
سال: 2012
ISSN: 0022-3069
DOI: 10.1097/nen.0b013e3182423c43